ON-GOING STUDY
TIMING OF CIRCADIAN SYNCHRONIZERS
The primary goal of this study is to determine if a circadian based intervention can help lower the health risks associated with habitual short sleep duration. Laboratory studies indicate short sleep duration can lead to circadian misalignment by altering the daily timing of light exposure, in turn, this misalignment can increase risk of cardiometabolic disease. This work will have important implications for developing treatments and countermeasures for people who are not able to get enough sleep (e.g., shift-workers, older adults, people with sleep disorders) with the goal of reducing their risk of diabetes and heart disease.
SLEEP EXTENSION AND CERAMIDES
The goal of this study is to determine the impact of a sleep extension intervention on plasma ceramides and insulin sensitivity in people with overweight and obesity and habitual short sleep duration. Ceramides are a type of fatty acid that can increase risk of diabetes and heart disease. If sleep extension can improve the profiles of ceramides and insulin sensitivity it could help establish sleep extension as an intervention to mitigate adverse disease risk.
NSYNC
The goal of this study is to determine how different light exposure patterns and food intake impact a person’s metabolism (how the body breaks down food) during short sleep duration. Several findings show short sleep duration is linked to risk of obesity and type 2 diabetes. Yet, there is a significant gap in our knowledge of potential mechanisms mitigating the adverse cardiometabolic risk of short sleep duration, impeding the development of effective interventions to mitigate such risk. This work will help inform novel interventions designed to promote circadian alignment during sleep loss, and thus improve cardiometabolic health in people with short sleep duration.
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PAST STUDIES
RESTORING ADEQUATE SLEEP DURATION
RADS is a research study investigating how sleep loss affects decision-making and your body’s ability to digest and process the foods you eat. Participants must be healthy adults, aged 18-35, who normally sleep less than 6.5 hours per night during the school/workweek.
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EFFECTS OF BEHAVIORAL SLEEP EXTENSION ON ALZHEIMER’S DISEASE RELEVANT BLOOD BIOMARKERS AND COGNITIVE PERFORMANCE
The goal of this study is to examine the impact of sleep extension on Alzheimer’s Disease related biomarkers and cognitive performance measures.
TIMING OF RESISTANCE EXERCISE
The goal of this study is to examine the influence of AM versus PM resistance exercise on risk of type 2 diabetes in older adults.
